Are you talking about the small notch that lines up with that casting seam that goes in a straight line between the cylinder, across the cam journal to the opposing lifter bore? I don't recall seeing any casting seams that noticeable in the past but I suspect that's all they are. Obviously not clearance notches for stroker or anything of the sort. Just looks like a casting seam to me. If the block checks OK, I don't think I would worry too much about them but you might want to hit them with a grinder just to reduce the chance of a stress riser in the area.